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Pharmaceuticals, 16(5), 676

doi: 10.1128/iai.61.4.1307-1314.1993 26 KosikowskaP.Berlicki

The most accepted theory is that AD is caused by misfolded proteins and the culprit in this misfolding is A peptides, that aggregate or clump, killing brain cells and giving rise to the symptoms of memory loss and reduced cognition

We showed that RIPK3 inhibition by dabrafenib significantly attenuated APAP and rhHMGB1-induced HepaRG cell death without interference with APAP bioactivation (Suppl Fig